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Select item 68526941.

The Fate of Copper Added to Surface Water: Field, Laboratory, and Modeling Studies

Kevin J. Rader, Richard F. Carbonaro, Eric D. van Hullebusch, Stijn Baken, Katrien Delbeke

Environ Toxicol Chem. 2019 Jul; 38(7): 1386–1399. Published online 2019 Jun 24. doi: 10.1002/etc.4440

PMCID:: PMC6852694

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Synthetic Fe/Cu Complexes: Toward Understanding Heme-Copper Oxidase Structure and Function

Suzanne M. Adam, Gayan B. Wijeratne, Patrick J. Rogler, Daniel E. Diaz, David A. Quist, Jeffrey J. Liu, Kenneth D. Karlin

Chem Rev. Author manuscript; available in PMC 2019 Nov 28.

Published in final edited form as: Chem Rev. 2018 Nov 28; 118(22): 10840–11022. Published online 2018 Oct 29. doi: 10.1021/acs.chemrev.8b00074

PMCID:: PMC6360144

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The Role of Copper Homeostasis in Brain Disease

Yumei An, Sunao Li, Xinqi Huang, Xueshi Chen, Haiyan Shan, Mingyang Zhang

Int J Mol Sci. 2022 Nov; 23(22): 13850. Published online 2022 Nov 10. doi: 10.3390/ijms232213850

PMCID:: PMC9698384

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The Use of Copper as an Antimicrobial Agent in Health Care, Including Obstetrics and Gynecology

Linda P. Arendsen, Ranee Thakar, Abdul H. Sultan

Clin Microbiol Rev. 2019 Oct; 32(4): e00125-18. Published online 2019 Aug 14. doi: 10.1128/CMR.00125-18

PMCID:: PMC6730497

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From Laboratory Research to a Clinical Trial: Copper Alloy Surfaces Kill Bacteria and Reduce Hospital-Acquired Infections

Harold T. Michels, C. William Keevil, Cassandra D. Salgado, Michael G. Schmidt

HERD. 2015 Oct; 9(1): 64–79. Published online 2015 Jul 10. doi: 10.1177/1937586715592650

PMCID:: PMC4561453

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Select item 93027756.

Copper microenvironments in the human body define patterns of copper adaptation in pathogenic bacteria

Francesca Focarelli, Andrea Giachino, Kevin John Waldron

PLoS Pathog. 2022 Jul; 18(7): e1010617. Published online 2022 Jul 21. doi: 10.1371/journal.ppat.1010617

PMCID:: PMC9302775

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Copper Dyshomeostasis in Neurodegenerative Diseases—Therapeutic Implications

Grażyna Gromadzka, Beata Tarnacka, Anna Flaga, Agata Adamczyk

Int J Mol Sci. 2020 Dec; 21(23): 9259. Published online 2020 Dec 4. doi: 10.3390/ijms21239259

PMCID:: PMC7730516

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Connecting copper and cancer: from transition metal signalling to metalloplasia

Eva J. Ge, Ashley I. Bush, Angela Casini, Paul A. Cobine, Justin R. Cross, Gina M. DeNicola, Q. Ping Dou, Katherine J. Franz, Vishal M. Gohil, Sanjeev Gupta, Stephen G. Kaler, Svetlana Lutsenko, Vivek Mittal, Michael J. Petris, Roman Polishchuk, Martina Ralle, Michael L. Schilsky, Nicholas K. Tonks, Linda T. Vahdat, Linda Van Aelst, Dan Xi, Peng Yuan, Donita C. Brady, Christopher J. Chang

Nat Rev Cancer. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Nat Rev Cancer. 2022 Feb; 22(2): 102–113. Published online 2021 Nov 11. doi: 10.1038/s41568-021-00417-2

PMCID:: PMC8810673

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Copper-Promoted Functionalization of Organic Molecules: from Biologically Relevant Cu/O₂ Model Systems to Organometallic Transformations

Rachel Trammell, Khashayar Rajabimoghadam, Isaac Garcia-Bosch

Chem Rev. Author manuscript; available in PMC 2019 Jun 15.

Published in final edited form as: Chem Rev. 2019 Feb 27; 119(4): 2954–3031. Published online 2019 Jan 30. doi: 10.1021/acs.chemrev.8b00368

PMCID:: PMC6571019

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Copper signalling: causes and consequences

Julianna Kardos, László Héja, Ágnes Simon, István Jablonkai, Richard Kovács, Katalin Jemnitz

Cell Commun Signal. 2018; 16: 71. Published online 2018 Oct 22. doi: 10.1186/s12964-018-0277-3

Correction in:: Cell Commun Signal. 2018; 16: 80.

PMCID:: PMC6198518

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Critical Review of Exposure and Effects: Implications for Setting Regulatory Health Criteria for Ingested Copper

Alicia A. Taylor, Joyce S. Tsuji, Michael R. Garry, Margaret E. McArdle, William L. Goodfellow, Jr., William J. Adams, Charles A. Menzie

Environ Manage. 2020; 65(1): 131–159. Published online 2019 Dec 12. doi: 10.1007/s00267-019-01234-y

Correction in:: Environ Manage. 2022; 69(5): 1051.

PMCID:: PMC6960211

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Copper(II) import and reduction are dependent on His-Met clusters in the extracellular amino terminus of human copper transporter-1

Sumanta Kar, Samarpita Sen, Saptarshi Maji, Deepashri Saraf, Ruturaj, Rupam Paul, Sohini Dutt, Basudeb Mondal, Enrique Rodriguez-Boulan, Ryan Schreiner, Durba Sengupta, Arnab Gupta

J Biol Chem. 2022 Mar; 298(3): 101631. Published online 2022 Jan 26. doi: 10.1016/j.jbc.2022.101631

PMCID:: PMC8867124

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An Emerging Role of Defective Copper Metabolism in Heart Disease

Yun Liu, Ji Miao

Nutrients. 2022 Feb; 14(3): 700. Published online 2022 Feb 7. doi: 10.3390/nu14030700

PMCID:: PMC8838622

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Exploiting the vulnerable active site of a copper-only superoxide dismutase to disrupt fungal pathogenesis

Natalie G. Robinett, Edward M. Culbertson, Ryan L. Peterson, Hiram Sanchez, David R. Andes, Jeniel E. Nett, Valeria C. Culotta

J Biol Chem. 2019 Feb 22; 294(8): 2700–2713. Published online 2018 Dec 28. doi: 10.1074/jbc.RA118.007095

PMCID:: PMC6393590

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Decreased Expression of the Slc31a1 Gene and Cytoplasmic Relocalization of Membrane CTR1 Protein in Renal Epithelial Cells: A Potent Protective Mechanism against Copper Nephrotoxicity in a Mouse Model of Menkes Disease

Olga Haberkiewicz, Paweł Lipiński, Rafał R. Starzyński, Aneta Jończy, Patrycja Kurowska, Mateusz Ogórek, Aleksandra Bednarz, Sylwia Herman, Dawid Hatala, Paweł Grzmil, Zenon Rajfur, Zbigniew Baster, Małgorzata Lenartowicz

Int J Mol Sci. 2022 Oct; 23(19): 11441. Published online 2022 Sep 28. doi: 10.3390/ijms231911441

PMCID:: PMC9570402

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The N-Terminal Tail of Histone H3 Regulates Copper Homeostasis in Saccharomyces cerevisiae

Sakshi Singh, Rakesh Kumar Sahu, Raghuvir Singh Tomar

Mol Cell Biol. 2021 Feb; 41(2): e00210-20. Prepublished online 2020 Nov 30. Published online 2021 Jan 25. doi: 10.1128/MCB.00210-20

PMCID:: PMC8093488

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CHCA-1 is a copper-regulated CTR1 homolog required for normal development, copper accumulation, and copper-sensing behavior in Caenorhabditis elegans

Sai Yuan, Anuj Kumar Sharma, Alexandria Richart, Jaekwon Lee, Byung-Eun Kim

J Biol Chem. 2018 Jul 13; 293(28): 10911–10925. Published online 2018 May 21. doi: 10.1074/jbc.RA118.003503

PMCID:: PMC6052217

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Select item 904075118.

Mac1-Dependent Copper Sensing Promotes Histoplasma Adaptation to the Phagosome during Adaptive Immunity

Stephanie C. Ray, Chad A. Rappleye

mBio. 2022 Mar-Apr; 13(2): e03773-21. Published online 2022 Apr 11. doi: 10.1128/mbio.03773-21

PMCID:: PMC9040751

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Select item 925887019.

Interactions between copper homeostasis and the fungal cell wall affect copper stress resistance

Corinna Probst, Sarela Garcia-Santamarina, Jacob T. Brooks, Inge Van Der Kloet, Oliver Baars, Martina Ralle, Dennis J. Thiele, J. Andrew Alspaugh

PLoS Pathog. 2022 Jun; 18(6): e1010195. Published online 2022 Jun 23. doi: 10.1371/journal.ppat.1010195

PMCID:: PMC9258870

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Select item 541106020.

Gene expression patterns in the progression of canine copper-associated chronic hepatitis

Karen Dirksen, Bart Spee, Louis C. Penning, Ted S. G. A. M. van den Ingh, Iwan A. Burgener, Adrian L. Watson, Marian Groot Koerkamp, Jan Rothuizen, Frank G. van Steenbeek, Hille Fieten

PLoS One. 2017; 12(5): e0176826. Published online 2017 May 1. doi: 10.1371/journal.pone.0176826

PMCID:: PMC5411060

Article PDF–6.6M

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Figure 5Inhibition of oHSV efficacy by Copper and its rescue with ATN-224

Glioma cells were infected with rQnestin34.5 (MOI=0.1) and incubated with buffer ± Copper (1 mg/L). A) Fluorescence microscopic images of GFP positive Gli36ΔEGFR glioma cells. B) Percent cell survival of U251T3, X12-V2, and Gli36ΔEGFR was measured 48 hrs post infection with rQnestin34.5 incubated with or without copper by standard crystal violet assay. *: P < 0.05 compared to rQnestin34.5. C–E): ATN-224 rescues copper-mediated inhibition of oHSV infection, replication and glioma cell killing. C) Fluorescent microscopy images of GFP positive Gli36ΔEGFR glioma cells infected with rQnestin34.5 incubated with Copper ± ATN-224. D) Viral titers were measured in cells infected with rQnestin34.5 pre-incubated with or without Copper ± ATN-224, 48 hrs post infection. *: P < 0.05 compared to rQnestin34.5 + Copper. E) Survival of cells infected with rQnestin34.5 pre-incubated with or without Copper ± ATN-224, 48 hrs post infection. *: P < 0.05 compared to rQnestin34.5 + Copper.

Copper chelation enhances anti-tumor efficacy and systemic delivery of oncolytic HSV

Clin Cancer Res. ;18(18):4931-4941.
Figure 1

The impact of cadmium and copper on PAL activity of G. procumbens. Bars represents standard error of differences between the means. N = 15. Cd 2 = cadmium 2 mg/L; Cd 4 = cadmium 4 mg/L; Cu 70= copper 70 mg/L; Cu 140 = copper 140 mg/L; Cd 2 + Cu 70 = cadmium 2 mg/L + Copper 70 mg/L; Cd 2 + Cu 140 = cadmium 2 mg/L + copper 140 mg/L; Cd 4 + Cu 70 = cadmium 4 mg/L + copper 70 mg/L; Cd 4 + Cu 140 = cadmium 4 mg/L + copper 140 mg/L.

Effect of Cadmium and Copper Exposure on Growth, Secondary Metabolites and Antioxidant Activity in the Medicinal Plant Sambung Nyawa (Gynura procumbens (Lour.) Merr)

Molecules. 2017 Oct;22(10):1623.
Figure 3

The impact of cadmium and copper on FRAP activity of G. procumbens. Bars represents standard error of differences between the means. N = 15. Cd 2 = cadmium 2 mg/L; Cd 4 = cadmium 4 mg/L; Cu 70 = copper 70 mg/L; Cu 140 = copper 140 mg/L; Cd 2 + Cu 70 = cadmium 2 mg/L + copper 70 mg/L; Cd 2 + Cu 140 = cadmium 2 mg/L + copper 140 mg/L; Cd 4 + Cu 70 = cadmium 4 mg/L + copper 70 mg/L; Cd 4 + Cu 140 = cadmium 4 mg/L + copper 140 mg/L.

Effect of Cadmium and Copper Exposure on Growth, Secondary Metabolites and Antioxidant Activity in the Medicinal Plant Sambung Nyawa (Gynura procumbens (Lour.) Merr)

Molecules. 2017 Oct;22(10):1623.
Fig. 7Copper leaching to STW in the absence (A) and presence of 1 mg L−1 of free chlorine (B) for 182 days. (●) 57% copper alloy; (*) 79% copper alloy, (■) 87% copper alloy; (○) 96% copper alloy, (▲) elemental copper (100% copper). () Maximum copper concentration in DW as recommended by WHO/EU Directive 98/83/EC (2 mg L−1). () Maximum copper concentration in DW as recommended by EPA Standard (1.3 mg L−1). The detection limit of the analytical method used was 0.3 mg L−1. The assay was performed with three replicates.

The role of surface copper content on biofilm formation by drinking water bacteria

RSC Adv. 2019 Oct 7;9(55):32184-32196.

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standard copper (226205)
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Francisella tularensis subsp. holarctica strain B.85 NODE_33_length_22465_cov_12...
Francisella tularensis subsp. holarctica strain B.85 NODE_33_length_22465_cov_1232.96_ID_74706, whole genome shotgun sequence
gi|1320467143|gb|PKAG01000033.1||gn :PKAG01|NODE_33_length_22465_cov_1232.96_ID_74706

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